Journal of Biotechnology ISSN:0973-0109

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Recent advancement in Typhoid research - a review

K.H.Khan, Deepak Ganjewala K.V. Bhaskara Rao.
Advanced BioTech, volume:7 Issue 04: October 10, 2008
Typhoid fever is endemic in South and Central America, the Middle East, South East and Far East Asia and the Indian subcontinent. It is estimated that more than 33 million cases of typhoid fever occur annually causing more than 500,000 deaths. Salmonella organism are extensively distributed in nature and causing widespread of disease in men and animals. Salmonella enterica serotype typhi causes typhoid fever, which is classically characterized by fever, headache, rose-colored rash, abdominal pains, diarrhea, paradoxical bradycardia and various other symptoms. This article discuses and summarizes important work in the literature in response to the epidemiology of typhoid fever, salmonella related to international trade and use of animal model to study typhoid. In this communication, we also reviewed the pathogenesis of Salmonella organism, diagnosis of typhoid fever and its treatment. Vaccination in relation to typhoid fever has been also focused. This review will let the reader to have a retrospective study on typhoid in concerned with Salmonellae.
Author Affiliations
K.H.Khan1, Deepak Ganjewala2 K.V. Bhaskara Rao2.
1. Centre for Biotechonlogy, Jamia Hamraed, Hamraed University, New Delhi -110 062, India.
2. Lecturer, School of Biotechnology, Chemical and Biomedical Engineering, VIT University, Vellore -632 014, Tamil Nadu, India.
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