Custom Made Animals
The Magic of Transgenesis
Abstract
Transgenesis is the introduction of a foreign gene into an animal or plant cells such that it is stably maintained in a heritable manner. Animals on which transgenesis has been performed are called transgenic animals. These technologies don't produce new species but work within the established genetic framework of existing species to improve them. Mice were the first animals to be produced transgenically and still remain the favourites for such experiments. During recent years, however, transgenic techniques have been extended to other species including the rabbit, the cow, the pig, the goat, and the sheep. This article attempts to provide an overview of the methods involved in the production of transgenic animals and their applications therein. We have also tried to incorporate the various ethical and societal issues arising from the use of this technology.
Keywords: Transgenesis, Electroporation, Microinjection, Knockout mouse, Oncomouse, Chimeras.
Author : Mahamulkar S., Joshi V., Chavan A., Waghmare J., Waghmare S.
For Correspondence : E mail :jyotsna.waghmare@gmail.com
FULL ARTICLE PDF 417 KB
